AmaliyaIndra Mustika Setia PribadiYULSA INAYAHNING ADHI2024-11-202024-11-202022-07-12https://repository.unpad.ac.id/handle/kandaga/160110180127Introduction: There is a lot of literature on tobacco cigarettes that shows the effect of cigarette content in the altered of gingival inflammatory response. E-cigarettes and vapes is increasingly popular around the world due to various factors. Several studies have shown that vaping has a similarly damaging effect as cigarette smoking on the health of the periodontium, that is the altered of gingival inflammatory response. This literature review how the gingival inflammatory response in vaping users is compared to tobacco smokers and this literature is expected to provide additional information regarding the impact of vaping and tobacco smoking. Methods: This type of literature review uses a scoping review. PRISMA-Scr was used as a guideline to search and sort articles using the criteria. (P: Population) Tobacco smokers and vape users, (C: Concept) Gingival inflammatory response in vape users and tobacco smokers, (C: Context) Smokers and vape users of all age, male and female all over the world. Results: There were 6 articles, including 2 pilot studies, 2 cross-sectional studies, 1 case-control study, and 1 observational study. The research obtained shows that there is a change in the gingival inflammatory response of tobacco smokers and vape users as seen from the bleeding on probing (BOP), self-rated oral symptomps, and GCF volume as well as inflammatory mediators. Conclusion: Tobacco smoking and vaping have an effect on the gingival inflammatory response. The inflammatory response of tobacco smokers has a masking effect that disguises vaping inflammation, which has the potential to cause an impaired inflammatory response in the gingiva.Gingival inflammationgingival responsegingivitis