Browsing by Author "MUTHIA AULIA QISTY"

Now showing 1 - 1 of 1
  • No Thumbnail Available
    Item
    Nutritional Status of Patient with Reccurent Aphthous Stomatitis: A Systematic Review of Observational Study
    (2022-07-10) MUTHIA AULIA QISTY; Nanan Nur aeny; Indah Suasani Wahyuni
    Recurrent aphthous stomatitis (RAS) is an oral mucosal disease, one of the predisposing factors for RAS is nutritional deficiency. Parameters of nutritional status included anthropometry, dietary assessment, and serological examination. The nutritional status of RAS sufferers has good macronutrients but low micronutrients. The purpose of this study was to review the nutritional status of RAS patients worldwide and its relationship to the number of ulcers, diameter, severity, and frequency of RAS recurrence. The Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) guidelines were used in structuring this systematic review. The PICO (population, intervention, comparison, outcome) and Risk of Bias Assessment tool for Non-randomized Studies (RoBANS) were used. Of twelve research articles in this study, seven used the case-control method, four used a cross-sectional study, and 1 article used a retrospective study. All studies used blood samples, and 2 articles also used saliva samples. This study found vitamin D, B12, and E deficiencies in RAS patients and no lack of folate, iron, zinc, and vitamins A and C. Vitamin D deficiency has a significant relationship with increasing ulcers. The nutritional status of patients with RAS showed a micronutrient deficiency and its relationship with increasing ulcers.