Browsing by Author "REGITA NURJINGGAN AUDIANI"

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    Use of Subantimicrobial Dose Doxycycline as Adjunct Therapy in Periodontitis Patients (Rapid Review)
    (2022-07-08) REGITA NURJINGGAN AUDIANI; Budhi Cahya Prasetyo; Janti Rusyanti
    Introduction: Periodontitis is an inflammatory disease of periodontal tissue due to pathogenic microorganisms interacting with host responds. Treatment scaling and root planing have been established as the standard in treating periodontitis, but there are limitations. The combination of additional therapy using Subantimicrobial Dose Doxycycline (SDD) is needed to overcome the excessive host response so that it can produce better therapeutic results. This study aims to determine the development of science regarding using SDD as an adjunct therapy in periodontitis patients. Methods: Rapid review method with literature screening and selection using the PRISMA protocol. The search strategy was carried out on the PubMed, Science Direct, and ProQuest databases using keywords and Boolean operators according to predetermined inclusion and exclusion criteria. Results: Five articles reviewed showed various changes in clinical parameters and inflammatory mediators. Changes in parameters that are considered significant and insignificant but still offer a better direction. Conclusion: The whole article shows that SDD positively affects the periodontal tissue, as seen by the decrease in Probing Depth (PD), Clinical Attachment Level (CAL), Bleeding on Probing (BOP), Gingival Index (GI), Plaque Index (PI), Matrix Metalloproteinase (MMP) and Gingival Ctevicular Fluid (GCF) which play a significant role in periodontitis.