A Retrospective Study of the Prevalence of Herpes Simplex Virus and Herpes Zoster Virus Infection at RSUP Hasan Sadikin Bandung from 2007 until 2011

Abstract

Herpes simplex virus (HSV) and herpes zoster virus (HZV) are two members of the herpes virus family that can affect the oral mucosa. Following primary infection, the viruses remain latent and may reactivate if the immune system becomes compromised. These viruses can manifest orally and systematically and either localized or generalized. The purpose of this study was to know the prevalence and the site of manifestation of HSV and HZV infection, and the accompanying systemic disease in RSUP Hasan Sadikin Bandung from January 2007 until December 2011. The method of this study was descriptive retrospective using secondary data and literature study. Data were taken from medical records of patients in RSUP Hasan Sadikin Bandung, from January 2007 until December 2011. The results were then presented in table and graphs. The study’s result showed the prevalence of HSV infection from 2007-2011 was 6% while the prevalence of HZV infection was 46%. HSV infection affected frequently on head or neck, and HZV infection affected frequently on trunk. The systemic diseases involved in these viruses include malignancies, neoplasm, skin diseases, blood disorder, and nerve disorder. The conclusion of this study was the prevalence of HSV infection was low, while the prevalence of HZV infection was high. The optimal treatment strategies are needed for reducing the morbidity and mortality associated with HSV and HZV infection, especially in immunocompromised patients. Keyword: herpes simplex virus, herpes zoster virus, prevalence

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Keywords

herpes simplex virus, herpes zoster virus, prevalence

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