Apatite Formation on Zirconia (Y-TZP) Coated with Carbonate Apatite in Simulated Body Fluid
No Thumbnail Available
Date
2020-08-10
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Abstract. Various bioactive calcium phosphates such as hydroxyapatite (HA) and carbonate apatite
(CO3Ap) have been widely studied due to their biocompatibility and osteoconductivity when
implanted into bone defects. CO3Ap has the ability to adapt bone structure and induce bone
regeneration; so that it can be categorized as resorbable bioactive materials. CO3Ap induced much
stronger response such as cell adhesion and actin ring formation to osteoclast-like cells rather than
HA. The aim of this study is to evaluate the bioactivity on zirconia (Y-TZP) coated with CO3Ap using
simulated body fluid (SBF). Twenty Y-TZP ZrO2 disks with a 12-mm diameter and 1-mm thickness
were employed as the samples. The disks were divided into two groups which the control group
without CO3Ap coating and tested group with CO3Ap coating. Disks samples are dipped into CO3Ap
suspension for one minute and stored in 37°C incubator for 24 hours. The disks were soaked in SBF
for 1, 4, and 7 day(s) at 36.5°C. The obtained apatite crystals were characterized by scanning electron
microscopy (SEM). It was found that the apatite formation on the tested group was greater than the
control group. The EDS pattern showed the presence of Ca and P on the control and tested group after
SBF soaking, which indicate the apatite deposition on the disks’ surface. However, the Ca and P on
the tested group was higher compared to the control group. The formation of apatite layer on the
disks’ surface is bioactivity indicator of CO3Ap.
Description
Keywords
Zirconia, carbonate apatite, simulated body fluid