EFFECT OF GEDI (ABELMOSCHUS MANIHOT L.) LEAVES INFUSION 9%, 18%, AND 27% ON BLOOD HDL LEVEL IN HYPERLIPDEMIA-INDUCED RATS
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Date
2012-08-09
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Abstract
Gedi (Abelmoschus manihot L.) is a plant
which can be found in tropical country. The leaves are one of the important ingredients in Manado porridge especially
in tinutuan porridge. However, not much research has been done to investigate
the potency of Gedi leaves. The purpose of this research is to investigate the
effect of Gedi leaves in increasing blood HDL level.
This is a laboratory experimental research
using 30 Wistar rats which is then divided into 5 groups. All groups except the
control negative group were induced with high fat diet exogenously and
endogenously for 2 weeks. 3 groups were then fed with Gedi leaves infusion with
the infusion concentration of 9%, 18% and 27% for another 2 weeks. The rats
underwent blood HDL level testing before and after the treatment. The results
of this research are statistically tested by methods of One Way ANOVA.
The mean
difference between pretest and post-test in control groups, control positive
and negative is 1.47, 14.49 respectively. It shows a decline about 2.60% and
20.06% in these group. In group 3 that is given Gedi leaves infusion 9% the
mean difference is 19.42. This shows that the blood HDL level decreases
25.9%.In group 4, infusion 18%, the mean difference of this group is 22.99. There
is 30.2% decrease of HDL level. For group 5, infusion 27%, the mean difference
in this group is 14.32; it shows that there is 20.52% decrease of HDL level in
rats.
As a conclusion, Gedi leaves infusion has no
effect in increasing blood HDL level; in fact it decreases the HDL level.
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Keywords
Abelmoschus manihot L, HDL, Tidak ada keyword