Association between Comorbidities and COVID-19 in Pregnant Women at Dr. Hasan Sadikin General Hospital Bandung 2020-2021
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Date
2023-02-15
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Abstract
Objective: The study aimed to determine the association between comorbidities and COVID-19 in pregnant women at Dr. Hasan Sadikin General Hospital, Bandung, West Java, Indonesia.
Methods: We conducted a cross-sectional study between January 2020 and December 2021 involving 278 women aged 16-45 years, at Dr.Hasan Sadikin General Hospital, Bandung, Indonesia, which serves as the main West Java tertiary hospital and COVID-19 referral hospital. We collected information from the medical record on comorbidities such as hypertension, obesity, diabetes mellitus, and others. Logistic regression models were fitted, and odds ratios with 95% confidence intervals (OR, 95%CI) were estimated.
Result: Of the 278 data included in this study, 120 cases had comorbidities. Most patients were asymptomatic, 82%. Obesity is the most common comorbid proportion, 71%. Only hypertension comorbid showed a significant association with symptomatic or asymptomatic COVID-19 (p<0.05). Pregnant women with hypertension were six times more likely to show symptoms than those without hypertension. (Odds ratio 6.092; 95% CI, 3.103-11.962). Pregnant women with obesity were 1.8x more likely to show symptoms than those without obesity (Odds ratio 1.856; 95% Confidence Interval, 0.987-3.489). Pregnant women with comorbidities were at higher risk of cesarean section 55% and stillbirth 67%.
Conclusion: The domination of asymptomatic COVID-19 in pregnant women was found in this study. Hypertension comorbid has a significant association with COVID-19 symptoms. Maternal and neonatal outcomes appear to be influenced by maternal comorbidities.
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maternal health, comorbidities, COVID-19 infection