Identifying Factors of Pre-exposure Prophylaxis (PrEP) Drug Regimen in Bandung: A Cross-sectional
No Thumbnail Available
Date
2023-07-14
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Background: Health services for HIV/AIDS prevention is still an important challenge for Indonesia. Risk factors for HIV infection have been successfully adapted into PrEP eligibility criteria to maximize the impact of the program. The aim of the study is to identify sociodemographic and HIV–risk profile of PrEP to support the growing evidence in adjusting PrEP use to users’ needs based on their characteristics and sexual behaviour and could further optimize prevention strategy of PrEP program.
Patients and methods: This cross–sectional study analyzed secondary data on sociodemographic and HIV–risk profile among 359 participants who were using PrEP in Klinik Mawar and Puskesmas Garuda Bandung. Sociodemographic data were exctracted from electronic medical records, while other data were extracted from administered PrEP eligibility online questionnaire. Descriptive analysis on quantitative characteristics (measurable variables) involved the calculation of basic statistics. The normality of quantitative variable distribution was verified using the Shapiro–Wilk test at a significance level of P=0.05. This data were analyzed using SPSS version 25.
Result: A total of 359 PrEP users were included in the study. 156 participants were on daily (43.4%) and 203 (56.6%) participants were on event–driven regimen. The median age of participants using daily PrEP (26 [IQR 18¬–51]) is comparable with participants using event–driven PrEP (27[IQR 18–51]). All of event–driven PrEP users were male, and less than 40% daily PrEP users were female. Most participants had a high school degree or lower (n=195, 73.2%) and employed (90.9%).The proportion of at–risk group comparing both regimen in this study were reported MSM (98.7% vs 67.5%), smallest proportion came from Transgender Women (TGW) (1.3% vs 7.9%). More than half (50.2%) daily PrEP users had 4 or more sexual partners. The greater proportion of participants who had HIV–positive or unknown sexual partners were reported in event–driven (75%) and daily (74.9%) regimen. Inconsistent use of condom was found higher in event–driven (60.3%) and daily (63.5%).
Conclusions: The overall characteristics and sexual behavior of PrEP users were similar except for higher numbers of sexual partners in daily than event–driven regimen.
Keywords: sociodemographic, sexual behaviour, pre-exposure prophylaxis, event–driven PrEP, daily PrEP
Description
Keywords
sociodemographic, sexual behaviour, pre-exposure prophylaxis